January 2025 PubMed Articles

The Alpha-1 Foundation is proud to provide a monthly list of articles from researchers that have been funded by the Foundation.

Below are the top articles for January 2025:

Alpha-1-Antitrypsin Deficiency Targeted Testing and Augmentation Therapy: A Canadian Thoracic Society Meta-analysis and Clinical Practice Guideline

• Kenneth Chapman 

Assessing Inflammatory Protein Biomarkers in COPD Subjects with and without Alpha-1 Antitrypsin Deficiency

• Brian Hobbs
• Auyon Gosh
• Russell Bowler
• David Lomas
• Dawn DeMeo

Response to risk of lung disease with the Pi*SS genotype of alpha-1 antitrypsin: the evidence in context

• Teresa Martin
• Marc Miravitlles

Is It Time Alpha-1 Antitrypsin Deficiency Had a Specific Patient Reported Outcome Measure? A Review

• Alice Turner

Inhaled alpha-1 antitrypsin (AAT) restores lower respiratory tract protease-antiprotease homeostasis and reduces inflammation in AAT-deficient individuals: a randomised phase 2 study

• Mark Brantly
• Jorge Lascano

Identification of an exosite at the neutrophil elastase/alpha-1-antitrypsin interface

• Riccardo Ronzoni
• David Lomas
• James Irving
• Annamaria Fra 

Alpha-1 Antitrypsin Inclusions Sequester GRP78 in a Bile Acid-Inducible Manner

• Marion Bouchecareilh
• Pavel Strnad

KF4 Anti-Chymotrypsin-like Elastase 1 Antibody and Purified Alpha-1 Antitrypsin Have Similar but Not Additive Efficacy in Preventing Emphysema in Murine Alpha-1 Antitrypsin Deficiency

• Briana Varisco

Improving the Likelihood of Identifying Alpha-1 Antitrypsin Deficiency Among Patients With COPD: A Novel Predictive Model Using Real-World Data

• Charlie Strange

Skewed adaptive immune responses are involved in alpha-1 antitrypsin deficiency emphysema

• Maria Basil
• Igor Barjaktarevic
• Andrew Wilson
• Francesca Polverino

Sex-Differences in Alpha-1 Antitrypsin Deficiency: Data from the EARCO Registry

• Alice Turner
• Marc Miravitlles
• Kenneth Chapman
• Miriam Barrecheguren

Increased risk of nonmelanoma skin cancer in patients with alpha-1 antitrypsin deficiency: A nationwide cohort study

• Morten Dahl

Alpha-1 Antitrypsin Mutation

• Timothy Craig