Finding a cure for Alpha-1 and improving the lives of those affected

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OUR IMPACT

We’ve invested over $100 million into Alpha‑1 research and related programs

From funding breakthrough research to hosting programs and events that keep our community strong and healthy until we find a cure, no other organization does more for families with Alpha‑1.

$100M

in research funded

130

researchers funded

10X

the clinical trials within a decade

TOP STORIES

Alpha-1 antitrypsin deficiency: A persistently underrecognized condition

Dr. James K. Stoller, a nationally recognized leader in Alpha-1 Antitrypsin Deficiency (Alpha-1), has published a new article in the […]

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March 3, 2026
RARE DISEASE DAY 2026 

Every February, the rare disease community comes together with a shared purpose: to raise awareness, inspire action, and amplify the […]

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March 2, 2026
February 2026 PubMed Articles

The Alpha-1 Foundation is proud to provide a monthly list of articles from researchers that have been funded by the […]

Read More… from February 2026 PubMed Articles

March 2, 2026
Medicare Drug Price Negotiation Program Engagement Opportunities

As you might have seen, CMS announced the next 15 drugs to go through the Medicare Drug Price Negotiation Program in late […]

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February 27, 2026
‘Substantially underdiagnosed’: Expert consensus moves to redefine rare liver disease 

“The continuation of achieving our goals hinges on detecting, testing, finding and helping every Alpha. We have increased our efforts […]

Read More… from ‘Substantially underdiagnosed’: Expert consensus moves to redefine rare liver disease 

February 26, 2026
FDA Launches Framework for Accelerating Development of Individualized Therapies for Ultra-Rare Diseases

FDA NEWS RELEASE The U.S. Food and Drug Administration today issued draft guidance for sponsors seeking approval for targeted individualized […]

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February 23, 2026
January 2026 PubMed Articles

The Alpha-1 Foundation is proud to provide a monthly list of articles from researchers that have been funded by the […]

Read More… from January 2026 PubMed Articles

February 2, 2026
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SPOTLIGHT

Finding Connection Through A1F Support Groups

South Carolina is welcoming two dedicated new A1F Support Group Leaders! Ronda Schilling, a former respiratory therapist who once cared for Alpha-1 patients and later received her own diagnosis, now brings both professional insight and personal experience to her role. She is joined by co-leader Jennifer Sherman, a professional counselor who supports individuals with chronic illness and is also living with Alpha-1.

Together, they are creating a supportive space where education and shared experience bring the Alpha-1 community closer. Their first meeting is Saturday, March 28, featuring Dr. Charlie Strange as guest speaker.

Find your local A1F Support Group

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