A1F Riding for a Reason

A1F Riding for a Reason is a nationwide movement that brings together the Alpha-1 community to raise funds and awareness for Alpha-1 Antitrypsin Deficiency (Alpha-1) through cycling. Whether you’re hitting the road in person or tracking miles virtually, every pedal forward helps advance the Alpha-1 Foundation’s mission of finding a cure for Alpha-1.

Throughout September, individuals and teams will ride in support of Alpha-1, whether for themselves or in honor of a loved one, uniting across the country with one goal: to make an impact.


Want to Participate In Person?

A1F Escape to the Cape

September 25–27 | Cape Cod, Massachusetts
Join Team Alpha-1 for one, two, or all three days of the A1F Escape to the Cape bike trek. Set along the scenic Cape Cod coastline, this event invites cyclists of all levels to ride and rally alongside the Alpha-1 community. It’s a fun-filled weekend of camaraderie, support, and purpose as we work together to raise critical funds and awareness.

We’re currently recruiting riders to help us cross the finish line and bring visibility to Alpha-1!

A1F Gulf Coast Bike Trek

October 17 | Dunedin, Florida
Join Team Alpha-1 in person for the 3rd Annual Gulf Coast Bike Trek in Dunedin, Florida. Choose your adventure from a seasoned cyclist’s 62-mile loop, an adventure seeker’s 40-mile loop, or family-friendly treks with 25-mile and 10-mile route options.

We’re recruiting riders and volunteers for the weekend to help us cross the finish line together and raise funds and awareness for Alpha-1.


Prefer to Ride Virtually?

A1F Riding for a Reason

All September – Virtual
Take part in A1F Riding for a Reason from anywhere in the country! Whether you’re on a bike, e-bike, or foot pedal, set a personal goal and log your miles throughout September. Connect with fellow participants through weekly Zoom calls and share your progress using #A1FRidingforaReason on social media.

Every mile moves us closer to our mission. Whether you’re riding for yourself or in honor of someone you love, your efforts will help bring hope to the Alpha-1 community.

Download your A1F Riding for a Reason toolkit here.

These events are open to the public and are held in partnership with the American Lung Association. You can also keep on track with the Strava activity and fundraising phone app. Ready to ride? Let’s make every mile count.

For more information, please contact Angela McBride at amcbride@alpha1.org.