Finding a cure for Alpha-1 and improving the lives of those affected

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OUR IMPACT

We’ve invested over $100 million into Alpha‑1 research and related programs

From funding breakthrough research to hosting programs and events that keep our community strong and healthy until we find a cure, no other organization does more for families with Alpha‑1.

$100M

in research funded

130

researchers funded

10X

the clinical trials within a decade

TOP STORIES

A1F Honors Kenneth Irvine at the 2025 Bettina B. Irvine Golf Invitational  

On Wednesday, May 28th, Ken Irvine, Alpha-1 Foundation Board of Director and his son, Bill Irvine hosted the annual Bettina B. Irvine Invitational Classic […]

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June 3, 2025
The 2025 A1F National Conference Celebrates 30 Years

The Alpha-1 Foundation (A1F) is proud to host the 2025 A1f National Conference from June 6th thru June 8th in Miami, Florida. […]

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May 30, 2025
A1F recognizes 2025 Grant Award Recipients during ATS 

On Monday, May 19th, 2025, the Alpha-1 Foundation (A1F) hosted its annual A1F Grants Award Reception at the San Francisco […]

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May 23, 2025
Post-Event Recap: 2nd Annual Walk in Memory of Lorraine Cimino  

On Sunday, May 18, 2025, more than 100 participants gathered at the Red Devils Softball Field in Brooklyn, New York […]

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May 23, 2025
A1F Celebrates 30th Anniversary at 2025 ATS

Honoring Three Decades of Research & Collaboration  The Alpha-1 Foundation is enthusiastic to join the American Thoracic Society for the […]

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May 9, 2025
Cruising for a Cure: A Beautiful Night of Purpose and Progress  

On May 2, 2025, the Alpha-1 community came together on the serene waters of Lake Norman, North Carolina for Cruising […]

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May 7, 2025
PEOPLE Magazine Feature: Stranger Who Donated Liver to Young Boy Surprises Him at His First Communion

Richie Ramirez and his family have been proudly involved with the Alpha-1 Foundation Virtual Walk, walking under their team name, […]

Read More… from PEOPLE Magazine Feature: Stranger Who Donated Liver to Young Boy Surprises Him at His First Communion

May 6, 2025
Alpha-1 Foundation selected as one of the 2025 Best Nonprofits to Work For

FOR IMMEDIATE RELEASE  MAY 5, 2025- The Alpha-1 Foundation (A1F) was recently selected as the #2 overall of the 2025 […]

Read More… from Alpha-1 Foundation selected as one of the 2025 Best Nonprofits to Work For

May 5, 2025
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SPOTLIGHT

Alpha-1 Empowerment

DC Young will be a featured speaker during the Alpha-1 Empowerment Hour at the 2025 A1F National Conference, taking place Friday, June 6 at 10:15 AM ET. This session highlights Alpha journeys and will also feature Craig and Melanie Hamilton, Nora Kemmerer, and Chelsea Boring. It will be available both in-person and online.

An active advocate, peer guide, and support group leader, DC has empowered fellow Alphas since attending his first National Conference in 2003. He’s also been a dedicated voice for the community through years of advocacy, including participation in numerous Alpha-1 Foundation lobby days.

Register today to watch the Alpha-1 Empowerment hour at the 2025 A1F National Conference

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two children in Alpha-1 Foundation branded shirts wearing medals around their necks and posing for a photo