Finding a cure for Alpha-1 and improving the lives of those affected

Find an Alpha‑1 Specialist

Browse our database to find a doctor specializing in Alpha‑1. Filter by location or area of expertise to narrow down your search.

Get Started
patient consulting with doctor with clipboard with map of US in the background patient consulting with doctor with clipboard

OUR IMPACT

We’ve invested over $100 million into Alpha‑1 research and related programs

From funding breakthrough research to hosting programs and events that keep our community strong and healthy until we find a cure, no other organization does more for families with Alpha‑1.

$100M

in research funded

130

researchers funded

10X

the clinical trials within a decade

TOP STORIES

November 2024 PubMed Articles

The Alpha-1 Foundation is proud to provide a monthly list of articles from researchers that have been funded by the […]

Read More… from November 2024 PubMed Articles

December 20, 2024
Virginia Clark, MD: Understanding Fazirsiran’s Potential in AATD Liver Disease

Watch her video interview here. New data from the open-label extension of the phase 2b SEQUOIA study of fazirsiran support […]

Read More… from Virginia Clark, MD: Understanding Fazirsiran’s Potential in AATD Liver Disease

December 20, 2024
Alpha-1 Foundation signs-on to letter on Utilization Management in Medicare Part D

Full letter below: Dear Ms. Duran:  We are writing to underscore the importance of the Centers for Medicare & Medicaid […]

Read More… from Alpha-1 Foundation signs-on to letter on Utilization Management in Medicare Part D

December 12, 2024
Alpha-1 Foundation signs onto community support letter for the Rare Pediatric PRV Program

December 4, 2024 The Honorable Chuck SchumerMajority LeaderUnited States Senate322 Hart Senate Office BuildingWashington, D.C. 20510 The Honorable Mitch McConnellMinority […]

Read More… from Alpha-1 Foundation signs onto community support letter for the Rare Pediatric PRV Program

December 6, 2024
27th Gordon L. Snider (GLS) Critical Issues Workshop

Experimental Models of Alpha-1 Antitrypsin Deficiency Lung and Liver Disease The Alpha-1 Foundation joined with researchers, clinicians and industry partners […]

Read More… from 27th Gordon L. Snider (GLS) Critical Issues Workshop

December 6, 2024
2024 Alpha-1 Awareness Month: Week 4 Highlights

In late November, the Alpha-1 community gathered in person and virtually to share stories of hope, resilience, and progress. The […]

Read More… from 2024 Alpha-1 Awareness Month: Week 4 Highlights

December 4, 2024
AlphaNet Honors Past Chair Robert L. Greene, Jr. with $100,000 Donation to Alpha-1 Foundation

In recognition of his dedicated service to our Board and Alpha-1 Community, AlphaNet is proud to honor Immediate Past Chair […]

Read More… from AlphaNet Honors Past Chair Robert L. Greene, Jr. with $100,000 Donation to Alpha-1 Foundation

December 2, 2024
Read More

SPOTLIGHT

Strengthening the Pillars of Progress

As we approach the 30th anniversary of the Alpha-1 Foundation in 2025, we reflect on three decades of progress with immense gratitude and renewed determination. Your unwavering support has been the cornerstone of our journey, driving breakthroughs once thought unattainable.

Together, we’ve turned challenges into opportunities, advancing our mission to transform lives. This year, we invite you to join us in a vision shaped by four powerful pillars: Insight, Innovation, Investment, and Impact—guiding our efforts toward a brighter future for those we serve.

Donate Today

Be the first to know about

Alpha-1 news & events near you

Help us end Alpha‑1 for everyone.

Your gift today brings us closer to a world without Alpha‑1.

Donate Now
two children in Alpha-1 Foundation branded shirts wearing medals around their necks and posing for a photo