Finding a cure for Alpha-1 and improving the lives of those affected

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OUR IMPACT

We’ve invested over $100 million into Alpha‑1 research and related programs

From funding breakthrough research to hosting programs and events that keep our community strong and healthy until we find a cure, no other organization does more for families with Alpha‑1.

$100M

in research funded

130

researchers funded

10X

the clinical trials within a decade

TOP STORIES

International Researchers Gather for Alpha-1 Foundation Investigators’ Meeting

Researchers from institutions across the United States, United Kingdom, Ireland, and Australia gathered this October for the 2026 Alpha-1 Foundation […]

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October 27, 2026
November Is Alpha-1 Awareness Month: The Future of Alpha-1 Is You 

The Alpha-1 Foundation (A1F) is proud to recognize November as Alpha-1 Awareness Month, a 30-day initiative that encourages the Alpha-1 […]

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October 26, 2026
FDA Launches Initiative to Advance Rare Disease Drug Development

The U.S. Food and Drug Administration, a division within the U.S. Department of Health and Human Services (HHS), today announced […]

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October 21, 2026
Annual Alpha-1 Gulf Coast Bike Trek Unites the Alpha-1 Community and Raises Awareness 

For the third consecutive year, Team Alpha-1 joined the American Lung Association (ALA) Gulf Coast Bike Trek, in Dunedin, Florida […]

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October 21, 2026
A New Hope for Gene Editing

Creating viable permanent cures for genetic disease has proved challenging, but some promising treatments are coming. By Gary Sernovitz Three years […]

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October 21, 2026
A1F Riding for a Reason 2026: Community, Commitment, and Resilience on Cape Cod 

From September 25–27, riders and volunteers joined the Alpha-1 Foundation’s (A1F) Team Alpha-1 and the American Lung Association (ALA) in […]

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October 8, 2026
A1F honors International Plasma Awareness Week 2026

Behind every plasma-derived therapy are hundreds of generous donors. A person with Alpha-1 Antitrypsin Deficiency (Alpha-1) needs about 900 plasma […]

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October 8, 2026
A1F Leadership and Scientific Summit 2026

The Alpha-1 Foundation (A1F) welcomed researchers, clinicians, Alpha-1 Support Group Leaders, and A1F leadership to Miami, Florida, for the biennial […]

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October 8, 2026
September 2026 PubMed Articles

The Alpha-1 Foundation (A1F) is proud to provide a monthly list of articles from researchers that have been funded by […]

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October 5, 2026
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SPOTLIGHT

Alphas and their caregivers raise Alpha-1 Awareness

As an Alpha-1 caregiver, Amber Simmons supported her mother, Deb LaBud, alongside her father, Tony. “Being her caregiver was a privilege I will forever be grateful for, even on the days when it was hard, scary, and emotionally exhausting. If I could do it all over again, I would choose to walk beside her every single time.”

This November, Amber is honoring Deb’s strength and legacy through the A1F Virtual Walk (#A1FVW26) with her team, “25 Years of Breath – Forever Our Lung Warrior.” Walk in honor of someone special, in memory of a loved one, or for yourself as we Step Forward for Alpha-1 together.

Register for the Virtual Walk

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