Finding a cure for Alpha-1 and improving the lives of those affected

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OUR IMPACT

We’ve invested over $100 million into Alpha‑1 research and related programs

From funding breakthrough research to hosting programs and events that keep our community strong and healthy until we find a cure, no other organization does more for families with Alpha‑1.

$100M

in research funded

130

researchers funded

10X

the clinical trials within a decade

TOP STORIES

April 2026 PubMed Articles

The Alpha-1 Foundation (A1F) is proud to provide a monthly list of articles from researchers that have been funded by […]

Read More… from April 2026 PubMed Articles

May 5, 2026
EU Alpha-1 Awareness Day 2026 

April 25, 2026 marks the ninth annual European Alpha-1 Awareness Day led by the Alpha-1 Europe Alliance, a date in which those afflicted with […]

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April 25, 2026
A1F joins Research Community in Strongly Opposing Proposed Cuts to NIH

The Alpha-1 Foundation (A1F) joined the 95 undersigned organizations, including patient advocacy groups, professional scientific and medical societies are profoundly […]

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April 17, 2026
March 2026 PubMed Articles

The Alpha-1 Foundation (A1F) is proud to provide a monthly list of articles from researchers that have been funded by […]

Read More… from March 2026 PubMed Articles

April 7, 2026
The Alpha-1 Foundation Mourns the Loss of Alpha Deborah LaBud 

It is with great sadness that we share the news that longtime Alpha-1 Foundation (A1F) supporter and AlphaNet coordinator Deborah (Debbie) LaBud […]

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April 3, 2026
A1F Building Friends for a Cure Training: A Weekend of Growing Together

Alpha-1 family members, friends, and caregivers from across the country came together for a meaningful and memorable Alpha-1 Foundation (A1F) Building Friends […]

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March 27, 2026
Beam Therapeutics Announces Update on BEAM-302

FOR IMMEDIATE RELEASE: Beam Therapeutics announced compelling updated clinical data from the ongoing Phase 1/2 trial of BEAM-302 in Alpha-1 […]

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March 25, 2026
The Celtic Connection 2026 

Happy St. Patrick’s Day! The Alpha-1 Foundation has been celebrating St. Patrick’s Day as a community since 2008. Over 300 guests joined together […]

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March 17, 2026
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SPOTLIGHT

Funding Promising Alpha-1 Research Through the A1F Grants Award Program

Matthew Moll, MD, is a current Alpha-1 Foundation In-Cycle Grants Program grantee. Through A1F’s Grants Award Program, Dr. Moll’s research focuses on leveraging genetics and other “omics” approaches to enable early identification and therapeutic interventions for Alpha-1 Antitrypsin Deficiency, advancing efforts to improve outcomes and move closer to a cure.

Most recently, he presented at the 29th Gordon L. Snider Critical Issues Workshop, where his talk, “Applying Omics Resources to Predict AATD Disease Outcomes,” highlighted how these technologies can help predict disease progression and identify new therapeutic targets.

Learn more about A1F's Grant Opportunities

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