December 2025 PubMed Articles

The Alpha-1 Foundation is proud to provide a monthly list of articles from researchers that have been funded by the Foundation. This list has the most A1F-funded researchers this year.

Below are the top articles for December 2025:

Multi-Society Expert Panel Consensus Guidance Regarding Clinical Assessment and Clinical Trial Endpoints in Adults With α-1 Antitrypsin Deficiency-Associated Liver Disease

• Scott Santarella
• Rohit Loomba
• Virginia Clark
• Mattias Mandorfer
• Marc Miravitles
• Mark Brantly
• Suzanne Sharpton
• Charlie Strange
• Alice Turner
• Hugo Vargas
• Pavel Strnad

Two Randomized Controlled Phase 2 Studies of the Oral Neutrophil Elastase Inhibitor Alvelestat in Alpha-1 Antitrypsin Deficiency

• Mike Wells
• Alice Turner
• Monica Goldklang
• Kenneth Chapman
• Jeanine D’Armiento
• Cheryl Pirozzi
• Brad Drummond
• Igor Barjaktarevic
• Charlie Strange 
• Robert Sandhaus
• Robert Stockley

Seasonal Changes in Circulating Alpha-1 Antitrypsin Are Altered by Sex and Genetic Deficiency

• Emma Leacy
• Mark Murphy
• Tomas Carroll
• Gerry McElvaney

In Response to Increased Risk of Cholesteatoma in Individuals with Alpha-1 Antitrypsin Deficiency: A Cohort Study

• Morton Dahl

Pulmonary Rehabilitation and Quality of Life in Alpha-1 Antitrypsin Deficiency: Findings From A Retrospective Cohort Study

• Paul Ellis
• Anita Pye
• Joshua de Souza

Rapid Design and Production of Alpha-1 Antitrypsin Fusion Proteins in a Plant-Based Cell-Free Expression System

• Karen McDonald
• Carroll Cross

Performance of Enhanced Liver Fibrosis Test and Indirect Serum Fibrosis Markers for Exclusion of Advanced Liver Fibrosis in Alpha-1 Antitrypsin Deficiency

• Malin Fromme
• Jan Stolk
• Ilaria Ferrarotti
• Pavel Strnad

Alvelestat for Alpha-1 Antitrypsin Deficiency-Associated Emphysema: The Hope for An Oral Treatment

• Marc Miravitlles

Clinical Features in Patients with Severe Alpha-1 Antitrypsin Deficiency Due to Rare Genotypesrrarotti

• Ilaria Ferrarotti