March & April 2024 PubMed Articles

The Alpha-1 Foundation is proud to provide a monthly list of articles from researchers that have been funded by the Foundation.

Below are the top articles for March and April 2024:

March 2024

Review article: New developments in biomarkers and clinical drug development in alpha-1 antitrypsin deficiency-related liver disease

• Rohit Loomba
• Ginger Clark
• Jeff Teckman
• Mark Brantly 
• Jeanine D’Armiento
• Alice Turner 
• Pavel Strnad

Improving the diagnosis of AATD with aid of serum protein electrophoresis: a prospective, multicentre, validation study

• Ilaria Ferrarotti

Computational Tools to Assist in Analyzing Effects of the SERPINA1 Gene Variation on Alpha-1 Antitrypsin (AAT)

• Joanna Chorostowska-Wynimko

Biodistribution and safety of a single rAAV3B-AAT vector for silencing and replacement of alpha-1 antitrypsin in Cynomolgus macaques

• Christian Mueller 
• Terence R. Flotte

Characteristics associated with SF-36 in alpha-1 antitrypsin deficiency-associated COPD: a cross-sectional analysis

• Robert A. Sandhaus
• Charlie Strange 

Cardiovascular disease in Alpha 1 antitrypsin deficiency: an observational study assessing the role of neutrophil proteinase activity and the suitability of validated screening tools

• Robert Stockley

April 2024

Alpha-1 Antitrypsin Deficiency

• Francisco Dasi

Impact of PNPLA3 I148M on alpha-1 antitrypsin deficiency-dependent liver disease progression

• Pavel Strnad

Genetic epidemiology of alpha-1 antitrypsin deficiency in Macaronesia

• Marc Miravitlles

Long-Term SGRQ Stability in a Cohort of Individuals with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease

• Robert A. Sandhaus
• Charlie Strange

Efficacy and safety of the Spiration Valve System™ for the treatment of severe emphysema in patients with Alpha-1 antitrypsin deficiency (EMPROVE)

• Kyle Hogarth

Reply to Chan: Identification of Alpha-1 Antitrypsin-Deficient Subjects with Normal Spirometry Who May Benefit from Alpha-1 Antitrypsin Replacement

• Auyon J. Gosh
• Tomas Carroll
• Gerry McElvaney