July 2024 PubMed Articles

The Alpha-1 Foundation is proud to provide a monthly list of articles from researchers that have been funded by the Foundation.

Below are the top articles for July 2024:

Sex-Differences in Alpha-1 Antitrypsin Deficiency: Data From the EARCO Registry. 

• Alice M. Turner
• Marc Miravitlles
• Ken Chapman

Alcohol consumption and liver phenotype of individuals with alpha-1 antitrypsin deficiency 

• Marc Miravitlles
• Alice m. Turner
• Pavel Strnad

A Further Step Toward Possible Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease.

• Vera Hupertz

Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by LRRK2 inhibitors.

• Riccardo Ronzoni
• James A. Irving 
• David Lomas
• Tamir Rashid

A novel in vitro cell model of the proteinase/antiproteinase balance observed in alpha-1 antitrypsin deficiency.      

• Elizabeth Sapey 
• Robert Stockley

Fazirsiran for Adults With Alpha-1 Antitrypsin Deficiency Liver Disease: A Phase 2 Placebo Controlled Trial (SEQUOIA). 

• Virginia Clark 
• Charlie Strange 
• Pavel Strnad
• Igor Barjaktarevic
• Monica Goldklang
• Meagan Gray 
• Brooks Kuhn 
• Mark Brantly 
• Rohit Loomba

Analysis of alpha-1-antitrypsin (AAT)-regulated, glucocorticoid receptor-dependent genes in macrophages reveals a novel host defense function of AAT. 

• Robert Sandhaus

Association of circulating Z-polymer with adverse clinical outcomes and liver fibrosis in adults with alpha-1 antitrypsin deficiency. 

• Pavel Strnad

Retrospective Database Analysis of Liver-Related Clinical Events in Adult and Pediatric Patients with Alpha-1 Antitrypsin Deficiency in the United States. 

• Charlie Strange

Improving the diagnosis of AATD with aid of serum protein electrophoresis: a prospective, multicentre, validation study. 

• Ilaria Ferrarotti